The purpose of the present study was to compare the international normalized ratio with a chromogenic factor X (CFX) assay for monitoring patients on oral anticoagulant therapy using the DiaPharma CFX method on a STA-R Evolution coagulation analyzer. International normalized ratio values were correlated with the CFX for determining normal, subtherapeutic, therapeutic and supratherapeutic ranges...

1. Abstract 2. Introduction 3. Experimental procedures 3.1. Reagents 3.2. Apparatus 3.3. Electrode preparation 4. Results and discussion 4.1. Preparation and characteristics of nano-SnO2 4.1.1. The preparation of nanoSnO2 4.1.2. The characteristics of nano-SnO2 4.2. Electrochemical behaviors of CFX at the nano-SnO2 modified electrode 4.2.1. Cyclic voltammograms of CFX at various modified electr...

OBJECTIVES Cefixime (Cfx), is a semi-synthetic third-generation oral cephalosporin antibiotic that is prescribed for the treatment of susceptible infections. There are some procedures for the determination of Cfx in pharmaceutical formulations and biological samples. Herein a spectrofluorimetric method was proposed for Cfx determination based on the fluorescence quenching of terbium-danofloxaci...

Intestinal absorption of beta-lactamine antibiotics (e.g., cefixime and cephalexin) has been shown to proceed through the dipeptide carrier system. In a previous study, nifedipine (NFP), an L-type calcium channel blocker, enhanced the absorption of cefixime in vivo but not in vitro, and it was suggested that neural mechanisms might be involved in the effect of NFP. The aim of the present study ...

Carbon monofluoride (CFx) has a high energy density, exceeding 2000 W h kg(-1), yet its application in primary lithium batteries is limited by its power capability. Multi-walled carbon nanotubes (CNTs) are appealing additives for high-power batteries, due to their outstanding electronic transport properties, high aspect ratio necessitating low volume fraction for percolation, and high tensile s...

Controlled release (CR) Ciprofloxacin (CFX) matrix tablets were prepared using Ciprofloxacin betaine as a model drug and Kollidon SR as a core matrix former. Kollidon SR embedded CFX matrix tablets were then characterized with Carbopol 974P NF, Cetyl alcohol, Hydroxypropyl methyl cellulose (HPMC 4.5 cps). CFX release was 74% after 10 hours dissolution in 0.01 N HCl solution from the tablets con...

This study aims to find the genotoxic and cytotoxic effects of a particular combination of pemetrexed (PMX) and cefixime (CFX) in human peripheral blood lymphocytes. Chromosome aberration (CA), sister chromatid exchange (SCE), and micronucleus (MN) tests were used to assess genotoxicity. Whereas, the cytotoxicity was evaluated by using mitotic index (MI), proliferation index (PI), and nuclear d...